听力与言语-语言病理学

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医学伦理学

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  • The effects of categorical and linguistic adaptation on binocular rivalry initial dominance.

    abstract::Binocular rivalry (BR) is a phenomenon in which visual perception alternates between two different monocular stimuli. There has been a long debate regarding its nature, with a special emphasis on whether low- or high-level mechanisms are involved. Prior adaptation to one of the two monocular stimuli is known to affect...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00187

    authors: Pelekanos V,Roumani D,Moutoussis K

    更新日期:2012-01-11 00:00:00

  • Brain activity patterns uniquely supporting visual feature integration after traumatic brain injury.

    abstract::Traumatic brain injury (TBI) patients typically respond more slowly and with more variability than controls during tasks of attention requiring speeded reaction time. These behavioral changes are attributable, at least in part, to diffuse axonal injury (DAI), which affects integrated processing in distributed systems....

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00164

    authors: Raja Beharelle A,Tisserand D,Stuss DT,McIntosh AR,Levine B

    更新日期:2011-12-09 00:00:00

  • Cortical microcircuit dynamics mediating binocular rivalry: the role of adaptation in inhibition.

    abstract::Perceptual bistability arises when two conflicting interpretations of an ambiguous stimulus or images in binocular rivalry (BR) compete for perceptual dominance. From a computational point of view, competition models based on cross-inhibition and adaptation have shown that noise is a crucial force for rivalry, and ope...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00145

    authors: Theodoni P,Panagiotaropoulos TI,Kapoor V,Logothetis NK,Deco G

    更新日期:2011-11-28 00:00:00

  • The human likeness dimension of the "uncanny valley hypothesis": behavioral and functional MRI findings.

    abstract::The uncanny valley hypothesis (Mori, 1970) predicts differential experience of negative and positive affect as a function of human likeness. Affective experience of humanlike robots and computer-generated characters (avatars) dominates "uncanny" research, but findings are inconsistent. Importantly, it is unknown how o...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00126

    authors: Cheetham M,Suter P,Jäncke L

    更新日期:2011-11-24 00:00:00

  • A combined robotic and cognitive training for locomotor rehabilitation: evidences of cerebral functional reorganization in two chronic traumatic brain injured patients.

    abstract::It has been demonstrated that automated locomotor training can improve walking capabilities in spinal cord-injured subjects but its effectiveness on brain damaged patients has not been well established. A possible explanation of the discordant results on the efficacy of robotic training in patients with cerebral lesio...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00146

    authors: Sacco K,Cauda F,D'Agata F,Duca S,Zettin M,Virgilio R,Nascimbeni A,Belforte G,Eula G,Gastaldi L,Appendino S,Geminiani G

    更新日期:2011-11-23 00:00:00

  • The neural basis of implicit perceptual sequence learning.

    abstract::The present fMRI study investigated the neural areas involved in implicit perceptual sequence learning. To obtain more insight in the functional contributions of the brain areas, we tracked both the behavioral and neural time course of the learning process, using a perceptual serial color matching task. Next, to inves...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00137

    authors: Gheysen F,Van Opstal F,Roggeman C,Van Waelvelde H,Fias W

    更新日期:2011-11-11 00:00:00

  • Functional Brain Network Characterization and Adaptivity during Task Practice in Healthy Volunteers and People with Schizophrenia.

    abstract::Cognitive remediation involves task practice and may improve deficits in people suffering from schizophrenia, but little is known about underlying neurophysiological mechanisms. In people with schizophrenia and controls, we used magnetoencephalography (MEG) to examine accuracy and practice-related changes in parameter...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00081

    authors: Weiss SA,Bassett DS,Rubinstein D,Holroyd T,Apud J,Dickinson D,Coppola R

    更新日期:2011-08-17 00:00:00

  • True and false recognition memories of odors induce distinct neural signatures.

    abstract::Neural bases of human olfactory memory are poorly understood. Very few studies have examined neural substrates associated with correct odor recognition, and none has tackled neural networks associated with incorrect odor recognition. We investigated the neural basis of task performance during a yes-no odor recognition...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00065

    authors: Royet JP,Morin-Audebrand L,Cerf-Ducastel B,Haase L,Issanchou S,Murphy C,Fonlupt P,Sulmont-Rossé C,Plailly J

    更新日期:2011-07-21 00:00:00

  • Distinct Inter-Joint Coordination during Fast Alternate Keystrokes in Pianists with Superior Skill.

    abstract::Musical performance requires motor skills to coordinate the movements of multiple joints in the hand and arm over a wide range of tempi. However, it is unclear whether the coordination of movement across joints would differ for musicians with different skill levels and how inter-joint coordination would vary in relati...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00050

    authors: Furuya S,Goda T,Katayose H,Miwa H,Nagata N

    更新日期:2011-05-27 00:00:00

  • The dopamine agonist bromocriptine differentially affects fronto-striatal functional connectivity during working memory.

    abstract::We investigated the effect of bromocriptine, a dopamine agonist, on individual differences in behavior as well as frontal-striatal connectivity during a working memory task. After dopaminergic augmentation, frontal-striatal connectivity in low working memory capacity individuals increases, corresponding with behaviora...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00032

    authors: Wallace DL,Vytlacil JJ,Nomura EM,Gibbs SE,D'Esposito M

    更新日期:2011-03-31 00:00:00

  • Microstructural Parcellation of the Human Cerebral Cortex - From Brodmann's Post-Mortem Map to in vivo Mapping with High-Field Magnetic Resonance Imaging.

    abstract::The year 2009 marked the 100th anniversary of the publication of the famous brain map of Korbinian Brodmann. Although a "classic" guide to microanatomical parcellation of the cerebral cortex, it is - from today's state-of-the-art neuroimaging perspective - problematic to use Brodmann's map as a structural guide to fun...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00019

    authors: Geyer S,Weiss M,Reimann K,Lohmann G,Turner R

    更新日期:2011-02-18 00:00:00

  • The temporal evolution of electromagnetic markers sensitive to the capacity limits of visual short-term memory.

    abstract::An electroencephalographic (EEG) marker of the limited contents of human visual short-term memory (VSTM) has previously been described. Termed contralateral delay activity, this consists of a sustained, posterior, negative potential that correlates with memory load and is greatest contralateral to the remembered hemif...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2011.00018

    authors: Mitchell DJ,Cusack R

    更新日期:2011-02-15 00:00:00

  • Aberrant Effective Connectivity in Schizophrenia Patients during Appetitive Conditioning.

    abstract::It has recently been suggested that schizophrenia involves dysfunction in brain connectivity at a neural level, and a dysfunction in reward processing at a behavioral level. The purpose of the present study was to link these two levels of analyses by examining effective connectivity patterns between brain regions medi...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00239

    authors: Diaconescu AO,Jensen J,Wang H,Willeit M,Menon M,Kapur S,McIntosh AR

    更新日期:2011-01-17 00:00:00

  • Deconstructing the "resting" state: exploring the temporal dynamics of frontal alpha asymmetry as an endophenotype for depression.

    abstract::Asymmetry in frontal electrocortical alpha-band (8-13 Hz) activity recorded during resting situations (i.e., in absence of a specific task) has been investigated in relation to emotion and depression for over 30 years. This asymmetry reflects an aspect of endogenous cortical dynamics that is stable over repeated measu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00232

    authors: Allen JJ,Cohen MX

    更新日期:2010-12-29 00:00:00

  • Staying cool when things get hot: emotion regulation modulates neural mechanisms of memory encoding.

    abstract::During times of emotional stress, individuals often engage in emotion regulation to reduce the experiential and physiological impact of negative emotions. Interestingly, emotion regulation strategies also influence memory encoding of the event. Cognitive reappraisal is associated with enhanced memory while expressive ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00230

    authors: Hayes JP,Morey RA,Petty CM,Seth S,Smoski MJ,McCarthy G,Labar KS

    更新日期:2010-12-22 00:00:00

  • Cognitive control signals in posterior cingulate cortex.

    abstract::Efficiently shifting between tasks is a central function of cognitive control. The role of the default network - a constellation of areas with high baseline activity that declines during task performance - in cognitive control remains poorly understood. We hypothesized that task switching demands cognitive control to ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00223

    authors: Hayden BY,Smith DV,Platt ML

    更新日期:2010-12-06 00:00:00

  • Functional brain network changes associated with maintenance of cognitive function in multiple sclerosis.

    abstract::In multiple sclerosis (MS) functional changes in connectivity due to cortical reorganization could lead to cognitive impairment (CI), or reflect a re-adjustment to reduce the clinical effects of widespread tissue damage. Such alterations in connectivity could result in changes in neural activation as assayed by execut...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00219

    authors: Helekar SA,Shin JC,Mattson BJ,Bartley K,Stosic M,Saldana-King T,Montague PR,Hutton GJ

    更新日期:2010-11-22 00:00:00

  • The lesioned brain: still a small-world?

    abstract::The intra-arterial amobarbital procedure (IAP or Wada test) is used to determine language lateralization and contralateral memory functioning in patients eligible for neurosurgery because of pharmaco-resistant epilepsy. During unilateral sedation, functioning of the contralateral hemisphere is assessed by means of neu...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00174

    authors: Douw L,van Dellen E,Baayen JC,Klein M,Velis DN,Alpherts WC,Heimans JJ,Reijneveld JC,Stam CJ

    更新日期:2010-11-11 00:00:00

  • Selective theta-synchronization of choice-relevant information subserves goal-directed behavior.

    abstract::Theta activity reflects a state of rhythmic modulation of excitability at the level of single neuron membranes, within local neuronal groups and between distant nodes of a neuronal network. A wealth of evidence has shown that during theta states distant neuronal groups synchronize, forming networks of spatially confin...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00210

    authors: Womelsdorf T,Vinck M,Leung LS,Everling S

    更新日期:2010-11-02 00:00:00

  • The Saccadic Re-Centering Bias is Associated with Activity Changes in the Human Superior Colliculus.

    abstract::Being able to effectively explore our visual world is of fundamental importance, and it has been suggested that the straight-ahead gaze (primary position) might play a special role in this context. We employed fMRI in humans to investigate how neural activity might be modulated for saccades relative to this putative d...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00193

    authors: Krebs RM,Schoenfeld MA,Boehler CN,Song AW,Woldorff MG

    更新日期:2010-11-01 00:00:00

  • What do we gain from gamma? Local dynamic gain modulation drives enhanced efficacy and efficiency of signal transmission.

    abstract::Gamma oscillations in neocortex are hypothesized to improve information transmission between groups of neurons. We recently showed that optogenetic drive of fast-spiking interneurons (FS) at 40 Hz in mouse neocortex in vivo modulates the spike count and precision of sensory evoked responses. At specific phases of alig...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00185

    authors: Knoblich U,Siegle JH,Pritchett DL,Moore CI

    更新日期:2010-10-21 00:00:00

  • Early Neural Markers of Implicit Attitudes: N170 Modulated by Intergroup and Evaluative Contexts in IAT.

    abstract::The Implicit Association Test (IAT) is the most popular measure to evaluate implicit attitudes. Nevertheless, its neural correlates are not yet fully understood. We examined event related potentials (ERPs) in response to face- and word processing while indigenous and non-indigenous participants performed an IAT displa...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00188

    authors: Ibáñez A,Gleichgerrcht E,Hurtado E,González R,Haye A,Manes FF

    更新日期:2010-10-19 00:00:00

  • Differential influence of levodopa on reward-based learning in Parkinson's disease.

    abstract::The mesocorticolimbic dopamine (DA) system linking the dopaminergic midbrain to the prefrontal cortex and subcortical striatum has been shown to be sensitive to reinforcement in animals and humans. Within this system, coexistent segregated striato-frontal circuits have been linked to different functions. In the presen...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00169

    authors: Graef S,Biele G,Krugel LK,Marzinzik F,Wahl M,Wotka J,Klostermann F,Heekeren HR

    更新日期:2010-10-14 00:00:00

  • Mal-adaptation of event-related EEG responses preceding performance errors.

    abstract::Recent EEG and fMRI evidence suggests that behavioral errors are foreshadowed by systematic changes in brain activity preceding the outcome by seconds. In order to further characterize this type of error precursor activity, we investigated single-trial event-related EEG activity from 70 participants performing a modif...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00065

    authors: Eichele H,Juvodden HT,Ullsperger M,Eichele T

    更新日期:2010-08-10 00:00:00

  • The insular taste cortex contributes to odor quality coding.

    abstract::Despite distinct peripheral and central pathways, stimulation of both the olfactory and the gustatory systems may give rise to the sensation of sweetness. Whether there is a common central mechanism producing sweet quality sensations or two discrete mechanisms associated independently with gustatory and olfactory stim...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00058

    authors: Veldhuizen MG,Nachtigal D,Teulings L,Gitelman DR,Small DM

    更新日期:2010-07-21 00:00:00

  • Dopaminergic Control of Attentional Flexibility: Inhibition of Return is Associated with the Dopamine Transporter Gene (DAT1).

    abstract::Genetic variability related to the dopamine (DA) transporter gene (DAT1) has received increasing attention as a possible modulator of human cognition. The 9-repeat allele of the DAT1 gene is presumably associated with higher striatal DA levels than the 10-repeat allele, which might support inhibitory control functions...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00053

    authors: Colzato LS,Pratt J,Hommel B

    更新日期:2010-07-13 00:00:00

  • Component Neural Systems for the Creation of Emotional Memories during Free Viewing of a Complex, Real-World Event.

    abstract::To investigate the neural systems that contribute to the formation of complex, self-relevant emotional memories, dedicated fans of rival college basketball teams watched a competitive game while undergoing functional magnetic resonance imaging (fMRI). During a subsequent recognition memory task, participants were show...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00034

    authors: Botzung A,Labar KS,Kragel P,Miles A,Rubin DC

    更新日期:2010-05-18 00:00:00

  • A cognitive training intervention increases resting cerebral blood flow in healthy older adults.

    abstract::Healthy aging is typically accompanied by some decline in cognitive performance, as well as by alterations in brain structure and function. Here we report the results of a randomized, controlled trial designed to determine the effects of a novel cognitive training program on resting cerebral blood flow (CBF) and gray ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.016.2010

    authors: Mozolic JL,Hayasaka S,Laurienti PJ

    更新日期:2010-03-12 00:00:00

  • Scene complexity: influence on perception, memory, and development in the medial temporal lobe.

    abstract::Regions in the medial temporal lobe (MTL) and prefrontal cortex (PFC) are involved in memory formation for scenes in both children and adults. The development in children and adolescents of successful memory encoding for scenes has been associated with increased activation in PFC, but not MTL, regions. However, eviden...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/fnhum.2010.00021

    authors: Chai XJ,Ofen N,Jacobs LF,Gabrieli JD

    更新日期:2010-03-05 00:00:00

  • Training facilitates object recognition in cubist paintings.

    abstract::To the naïve observer, cubist paintings contain geometrical forms in which familiar objects are hardly recognizable, even in the presence of a meaningful title. We used fMRI to test whether a short training session about Cubism would facilitate object recognition in paintings by Picasso, Braque and Gris. Subjects, who...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.011.2010

    authors: Wiesmann M,Ishai A

    更新日期:2010-03-02 00:00:00

  • Differential development of the ventral visual cortex extends through adolescence.

    abstract::The ventral temporal cortex (VTC) in humans includes functionally defined regions that preferentially respond to objects, faces, and places. Recent developmental studies suggest that the face selective region in the fusiform gyrus ('fusiform face area', FFA) undergoes a prolonged development involving substantial incr...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.080.2009

    authors: Golarai G,Liberman A,Yoon JM,Grill-Spector K

    更新日期:2010-02-22 00:00:00

  • A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing.

    abstract::A review of the human developmental neuroimaging literature that investigates outcomes following exposure to psychosocial adversity is presented with a focus on two subcortical structures - the hippocampus and the amygdala. Throughout this review, we discuss how a consideration of developmental timing of adverse exper...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.068.2009

    authors: Tottenham N,Sheridan MA

    更新日期:2010-01-08 00:00:00

  • Electrophysiological correlates of learning-induced modulation of visual motion processing in humans.

    abstract::Training on a visual task leads to increased perceptual and neural responses to visual features that were attended during training as well as decreased responses to neglected distractor features. However, the time course of these attention-based modulations of neural sensitivity for visual features has not been invest...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.069.2009

    authors: Gál V,Kóbor I,Bankó EM,Kozák LR,Serences JT,Vidnyánszky Z

    更新日期:2010-01-06 00:00:00

  • Discordant Tasks and Motor Adjustments Affect Interactions between Adaptations to Altered Kinematics and Dynamics.

    abstract::Motor control and adaptation are multi-determinate processes with complex interactions. This is reflected for example in the ambiguous nature of interactions during sequential adaptation of reaching under kinematics and dynamics perturbations. It has been suggested that perturbations based on the same kinematic parame...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.065.2009

    authors: Arce F,Novick I,Vaadia E

    更新日期:2010-01-04 00:00:00

  • FMRI in translation: the challenges facing real-world applications.

    abstract::Functional neuroimaging has increased our understanding of human brain function tremendously and has become a standard tool in clinical and cognitive neuroscience research. We briefly review its methodological foundations and describe remaining challenges for translational research. The application of neuroimaging res...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.063.2009

    authors: Schleim S,Roiser JP

    更新日期:2009-12-23 00:00:00

  • Hand posture effects on handedness recognition as revealed by the simon effect.

    abstract::We investigated the influence of hand posture in handedness recognition, while varying the spatial correspondence between stimulus and response in a modified Simon task. Drawings of the left and right hands were displayed either in a back or palm view while participants discriminated stimulus handedness by pressing ei...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.059.2009

    authors: Lameira AP,Gawryszewski LG,Guimarães-Silva S,Ferreira FM,Vargas CD,Umiltà C,Pereira A

    更新日期:2009-11-30 00:00:00

  • Convergent approaches for defining functional imaging endophenotypes in schizophrenia.

    abstract::In complex genetic disorders such as schizophrenia, endophenotypes have potential utility both in identifying risk genes and in illuminating pathophysiology. This is due to their presumed status as closer in the etiopathological pathway to the causative genes than is the currently defining clinical phenomenology of th...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.037.2009

    authors: Pearlson GD,Calhoun VD

    更新日期:2009-11-24 00:00:00

  • BDNF Val66Met polymorphism influences age differences in microstructure of the Corpus Callosum.

    abstract::Brain-derived neurotrophic factor (BDNF) plays an important role in neuroplasticity and promotes axonal growth, but its secretion, regulated by a BDNF gene, declines with age. The low-activity (met) allele of common polymorphism BDNF val66met is associated with reduced production of BDNF. We examined whether age-relat...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.019.2009

    authors: Kennedy KM,Rodrigue KM,Land SJ,Raz N

    更新日期:2009-08-20 00:00:00

  • Perfusion imaging of the right perisylvian neural network in acute spatial neglect.

    abstract::Recent studies have suggested a tightly connected perisylvian neural network associated with spatial neglect. Here we investigated whether structural damage in one part of the network typically is accompanied with functional damage in other, structurally intact areas of this network. By combining normalized fluid-atte...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.015.2009

    authors: Zopf R,Fruhmann Berger M,Klose U,Karnath HO

    更新日期:2009-08-03 00:00:00

  • Using time-to-contact information to assess potential collision modulates both visual and temporal prediction networks.

    abstract::Accurate estimates of the time-to-contact (TTC) of approaching objects are crucial for survival. We used an ecologically valid driving simulation to compare and contrast the neural substrates of egocentric (head-on approach) and allocentric (lateral approach) TTC tasks in a fully factorial, event-related fMRI design. ...

    journal_title:Frontiers in human neuroscience

    pub_type: 杂志文章

    doi:10.3389/neuro.09.010.2008

    authors: Coull JT,Vidal F,Goulon C,Nazarian B,Craig C

    更新日期:2008-09-13 00:00:00

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